Lior Jankelson

I am a physician-scientist working at the intersection of cardiac electrophysiology, computational cardiology, biomedical engineering, and agentic AI. I serve as an Associate Professor of Medicine at NYU Grossman School of Medicine, an Associate Professor of Biomedical Engineering at NYU Tandon School of Engineering, an attending physician at NYU Langone Health, and Director of the Inherited Arrhythmia and Cardiovascular Genetics Program. I received my MD and PhD (biophysics) from the Technion Israel Institute of Technology. My work focuses on machine learning for the electrocardiogram, data analytics for electrophysiology and mapping systems, genetic cardiology, and the development of AI tools that improve diagnosis, intervention, and patient care.

lioryan at gmail dot com
Lior Jankelson
01 — Agentic Medicine

I am passionate about developing software products at the boundary of frontier applied AI and clinical workflows. Here are some examples:

VarCardio landing page
VarCardio
02 — EKG-AI

In my group, we develop cutting edge AI solution for EKG based prediction and classification. We focus on complex ideas and architectures sometimes required for rare conditions. We build end-to-end, algorithm-to-infra EKG-AI dashboards implemented in the EHR. You can find here some of our publications

EKG-AI dashboard
EKG-AI Dashboard
EHR integrated EKG-AI dashboard
EHR-Integrated Risk Dashboard
2025
Artificial intelligence-enabled sinus electrocardiograms for the detection of paroxysmal atrial fibrillation benchmarked against the CHARGE-AF score
European Heart Journal Digital Health
2025
Self-supervised VICReg pre-training for Brugada ECG detection
Scientific Reports
2024
QTNet: Predicting Drug-Induced QT Prolongation With Artificial Intelligence-Enabled Electrocardiograms
JACC: Clinical Electrophysiology
2024
Performance of Publicly Available Large Language Models on Internal Medicine Board-style Questions
PLOS Digital Health
adjacent clinical AI / model evaluation
2024
Performance of a Protein Language Model for Variant Annotation in Cardiac Disease
Journal of the American Heart Association
AI for cardiovascular genomics
2023
Development of an AI-Driven QT Correction Algorithm for Patients in Atrial Fibrillation
JACC: Clinical Electrophysiology
2023
Explainable SHAP-XGBoost models for in-hospital mortality after myocardial infarction
Cardiovascular Digital Health Journal
2021
Electrocardiographic Risk Stratification in COVID-19 Patients
Frontiers in Cardiovascular Medicine
2020
The QT interval in patients with COVID-19 treated with hydroxychloroquine and azithromycin
Nature Medicine
2020
QT interval prolongation and torsade de pointes in patients with COVID-19 treated with hydroxychloroquine/azithromycin
Heart Rhythm
2020
QT prolongation, torsades de pointes, and sudden death with short courses of chloroquine or hydroxychloroquine as used in COVID-19: A systematic review
Heart Rhythm
2020
Adversarial attacks and adversarial robustness in electrocardiogram deep learning systems
Nature Medicine
2019
Adversarial Examples for Electrocardiograms
arXiv
2022
New-Onset Diabetes Assessment Using Artificial Intelligence-Enhanced Electrocardiography
arXiv
arXiv author search result
03 — Biomedical Engineering

Device and procedural engineering work, including minimally invasive platforms and translational product development.

04 — Cardiac Electrophysiology & Inherited Arrhythmia

In my clinical role I am a cardiac electrophysiologist, directing the NYU Inherited Arrhythmia program. You can find here some of my work in these fields.

2026
Class Ic antiarrhythmic drugs and structural heart disease - time for a randomized controlled study?
Heart Rhythm
2025
Novel algorithm for fully automated rapid and accurate high definition electrogram acquisition for electroanatomical mapping
Journal of Interventional Cardiac Electrophysiology
2024
Conduction velocity is reduced in the posterior wall of hypertrophic cardiomyopathy patients with normal bipolar voltage undergoing ablation for paroxysmal atrial fibrillation
Journal of Interventional Cardiac Electrophysiology
2024
Risk of malignant ventricular arrhythmias in patients with mildly to moderately reduced ejection fraction after permanent pacemaker implantation
Heart Rhythm
2023
Persistent atrial fibrillation ablation: the ongoing search for the perfect wave
Journal of Interventional Cardiac Electrophysiology
2022
Outcomes of posterior wall isolation with pulmonary vein isolation for paroxysmal atrial fibrillation
Journal of Cardiovascular Electrophysiology
2022
Subcutaneous versus transvenous implantable defibrillator in patients with hypertrophic cardiomyopathy
Heart Rhythm
2021
Lesion Sequence and Catheter Spatial Stability Affect Lesion Quality Markers in Atrial Fibrillation Ablation
JACC: Clinical Electrophysiology
2020
Quantitative analysis of ablation technique predicts arrhythmia recurrence following atrial fibrillation ablation
American Heart Journal
2019
Reducing right ventricular pacing burden: algorithms, benefits, and risks
Europace
2019
Impact of RNA testing on cardiac variant interpretation and patient management
HeartRhythm Case Reports